Cosmetic applications of glucitol-core containing gallotannins from a proprietary phenolic-enriched red maple (Acer rubrum) leaves extract: inhibition of melanogenesis via down-regulation of tyrosinase and melanogenic gene expression in B16F10 melanoma cells

Hang Ma, Jialin Xu, Nicholas A DaSilva, Ling Wang, Zhengxi Wei, Liangran Guo, Shelby L Johnson, Wei Lu, Jun Xu, Qiong Gu, Navindra P Seeram

Antioxidant Activity & Environmental Defense

In Simple Terms:

Red maple leaf extract exhibits strong antioxidant activity, helping to protect skin cells from oxidative stress caused by environmental factors such as UV exposure and pollution.

Key Findings:

  • Oxidative stress markers reduced by up to 92.8%

  • High concentration of polyphenolic antioxidants

  • Supports cellular protection against environmental damage

Study Breakdown:

Oxidative stress occurs when free radicals damage skin cells, contributing to premature aging and structural breakdown.

Red maple leaf extract contains a dense concentration of polyphenols, which act as antioxidants to neutralize free radicals and reduce oxidative damage.

In controlled studies, oxidative stress markers were significantly reduced, demonstrating the extract’s ability to protect cellular structures from environmental damage.

Why It Matters for Your Skin:

Daily exposure to UV radiation and pollution accelerates skin aging.

By helping defend against oxidative stress, red maple leaf extract supports healthier, more resilient skin over time.